Santa María Department Accommodation: Find the Best Hotels in Santa María Department

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Top cities in Santa María Department

Santa Maria

San José

Loro Huasi

Casa de Piedra

Fuerte Quemado

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Our top choices for Santa María Department hotels

A rustic stone pathway leading to a wooden structure with a stone wall.

A room with wooden beams, a tiled floor, a bench, and a painting on the wall.

A rustic stone house with a wooden door and a small porch.

A dining area with a wooden table and chairs, a painting on the wall, and large windows with curtains.

1. Cerco del Trigo. Total peace

Cerco del Trigo. Total peace

Amaicha del Valle

The price is AU$113

AU$113

6 Nov - 7 Nov

Cerco del Trigo. Total peace

A rustic building with a stone facade, a flat roof, and a small window.

A room with a fireplace, a glass table, patterned rugs, and a staircase leading to another level.

A stone structure with a metal railing, overlooking a grassy field with trees and mountains in the distance.

A room with a tiled floor, a round table, two chairs, a sofa, a window with curtains, and a wall-mounted light fixture.

2. Hidden House in La Fronterita

Hidden House in La Fronterita

Amaicha del Valle

The price is AU$98

AU$98

6 Nov - 7 Nov

Hidden House in La Fronterita

3. Cabaña Achalay ALAMO – Refugio en Santa María

Cabaña Achalay ALAMO – Refugio en Santa María

Santa María

The price is AU$81

AU$81

6 Nov - 7 Nov

Cabaña Achalay ALAMO – Refugio en Santa María

4. Cabaña Achalay BREA – Refugio en Santa María

Cabaña Achalay BREA – Refugio en Santa María

Santa María

The price is AU$81

AU$81

6 Nov - 7 Nov

Cabaña Achalay BREA – Refugio en Santa María

An outdoor dining area with a table set for two, a bottle of white wine, and a view of mountains in the background.

A dining area with tables set for a meal, large windows, and a view of the landscape.

A hotel entrance with a stone facade, a triangular roof, and a sign reading "Altos de Amachuca Hotel Boutique."

A living room with a piano, a couch, a coffee table, and a guitar.

5. Hotel Boutique Altos de Amaicha

Hotel Boutique Altos de Amaicha

3.0 star property

Amaicha Del Valle

Hotel Boutique Altos de Amaicha

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Santa María Department Hotel Reviews

A swimming pool with lounge chairs and a gazebo, surrounded by a building with multiple windows and balconies.

A white building with a central arched entrance and a bell tower, surrounded by well-maintained gardens and a gravel pathway.

A table set with various dishes, wine glasses, and a bottle of wine.

A spacious dining area with a large table, chairs, and a chandelier. There is a view of a pool and mountains through large windows.

Patios de Cafayate - Wine Hotel & Restaurant

Cafayate

10/10 Excellent

Incredible stay! Loved our room, friendly staff and the restaurant was great. Did the winery tour and really enjoyed it. Highly recommend this charming hotel!

Tomas

Reviewed December 24, 2024Reviewed December 24, 2024

Patios de Cafayate - Wine Hotel & Restaurant

A well-lit residential area with a winding driveway, cacti, and a variety of trees.

A resort with multiple buildings, a swimming pool, and a mountainous backdrop.

A nighttime view of a resort entrance with a pool area, a statue, and a sign with the resort's name.

Piattelli Wine Resort

Cafayate

10/10 Excellent

The resort itself is beautiful. Gardens are stunning and it is set in incredibly scenic location. We enjoyed the complimentary wine tasting. Our casita was beautiful with a roof top terrace. Also enjoyed dinner there. Wished we could have stayed longer. Really good value for what you get. Highly recommended.

Johnny

Reviewed March 27, 2025Reviewed March 27, 2025

Piattelli Wine Resort

A pool area with a white building in the background, columns, and potted plants.

A water feature with a sign reading "Portal del Planto" and a potted plant nearby.

A building with white columns and balconies.

A covered outdoor seating area with a pool in the background.

Hotel Portal del Santo

Cafayate

10/10 Excellent

Really lovely place to stay. The owners are so friendly and helpful with recommendations and made sure we had their number Incase we needed anything while we were out. Beds are very comfortable and breakfast one of the better ones we have had on our travels. They make their own jams and breads :) definitely recommend

Jacqueline

Reviewed January 26, 2020Reviewed January 26, 2020

Hotel Portal del Santo

An outdoor patio with a fire pit surrounded by wooden chairs and a guitar, set on a cobblestone floor.

A buffet table with various food items and serving utensils.

A bicycle parked against a wall with a cobblestone ground, a yellow wall, and a blue door in the background.

A building with a balcony, stone base, and a door with an arch.

Villa Vicuña Hotel Boutique Cafayate

Cafayate

10/10 Excellent

The staff were friendly and hospitable. The courtyard is lovely and the buffet breakfast very good.

Jennifer

Reviewed February 21, 2025Reviewed February 21, 2025

Villa Vicuña Hotel Boutique Cafayate

An outdoor patio area with a dining table and chairs, a staircase, and a pergola covered with vines.

A restaurant with patterned flooring, wooden chairs, and tables.

A two-story building with a swimming pool, potted plants, and a balcony with a railing.

A hotel room with a bed, a nightstand, a wooden bench, a wall-mounted air conditioner, and a framed picture on the wall.

HOTEL PLAZA CAFAYATE

Cafayate

10/10 Excellent

Really liked this hotel, great cafe area for gathering / delicious breakfast, helpful staff. Can't beat the location

Jill

Reviewed January 26, 2026Reviewed January 26, 2026

HOTEL PLAZA CAFAYATE

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Book Santa María Department Hotels

Change your mind

Treat yourself

Be picky

Top cities in Santa María Department

Santa Maria

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santa María Department hotels

1. Cerco del Trigo. Total peace

2. Hidden House in La Fronterita

3. Cabaña Achalay ALAMO – Refugio en Santa María

4. Cabaña Achalay BREA – Refugio en Santa María

5. Hotel Boutique Altos de Amaicha

Top Santa María Department Hotel Reviews

Patios de Cafayate - Wine Hotel & Restaurant

10/10 Excellent

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